Frénel, Jean-Sébastien : rechercher sur Z-Library

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1

An open-label, dose-escalation study to evaluate the safety and pharmacokinetics of CEP-9722 (a PARP-1 and PARP-2 inhibitor) in combination with gemcitabine and cisplatin in patients with advanced solid tumors

Awada, Ahmad, Campone, Mario, Varga, Andrea, Aftimos, Philippe, Frenel, Jean-Sébastien, Bahleda, Rastilav, Gombos, Andrea, Bourbouloux, Emmanuelle, Soria, Jean-Charles

Journal:

Anti-Cancer Drugs

Année:

2016

Langue:

english

Fichier:

PDF, 209 KB

english, 2016

2

NY-ESO-1-Specific Circulating CD4+ T Cells in Ovarian Cancer Patients Are Prevalently TH1 Type Cells Undetectable in the CD25+FOXP3+Treg Compartment

Redjimi, Nassima, Duperrier-Amouriaux, Karine, Raimbaud, Isabelle, Luescher, Immanuel, Dojcinovic, Danijel, Classe, Jean-Marc, Berton-Rigaud, Dominique, Frenel, Jean-Sébastien, Bourbouloux, Emmanuelle

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 718 KB

english, 2011

3

Benefits versus risk profile of buparlisib for the treatment of breast cancer

Patsouris, Anne, Augereau, Paule, Frenel, Jean-Sebastien, Robert, Marie, Gourmelon, Carole, Bourbouloux, Emmanuelle, Berton-Rigaud, Dominque, Chevalier, Louise-Marie, Campone, Mario

Journal:

Expert Opinion on Drug Safety

Année:

2019

Langue:

english

Fichier:

PDF, 998 KB

english, 2019

4

Oxaliplatin-based hyperthermic intraperitoneal chemotherapy in primary or recurrent epithelial ovarian cancer: A pilot study of 31 patients

Jean-Sebastien Frenel, Christophe Leux, Luc Pouplin, Gwenael Ferron, Dominique Berton-Rigaud, Emmanuelle Bourbouloux, François Dravet, Isabelle Jaffre, Jean-Marc Classe

Journal:

Journal of Surgical Oncology

Année:

2011

Langue:

english

Fichier:

PDF, 89 KB

english, 2011

5

Clinical Insights: Neoadjuvant Therapy in Breast Cancer ||

Campone, Mario, Frenel, Jean-Sébastien

Année:

2014

Langue:

english

Fichier:

PDF, 2.23 MB

english, 2014

6

Clinical Insights: Neoadjuvant Therapy in Breast Cancer || Neoadjuvant therapy in breast cancer

Campone, Mario, Frenel, Jean-Sébastien

Année:

2014

Langue:

english

Fichier:

PDF, 356 KB

english, 2014

7

Place du trastuzumab emtansine dans le traitement systémique des métastases cérébrales du cancer du sein HER2+ : à propos de 5 cas et revue de la littérature

Frenel, Jean-Sébastien, Bally, Olivia, Bourbouloux, Emmanuelle, Berton-Rigaud, Dominique, Campone, Mario, Bachelot, Thomas, Heudel, Pierre-Étienne

Journal:

Bulletin du Cancer

Année:

2016

Langue:

french

Fichier:

PDF, 622 KB

french, 2016

8

Efficacy and safety of trastuzumab emtansine (T-DM1) in patients with HER2-positive breast cancer with brain metastases

Jacot, William, Pons, Elvire, Frenel, Jean-Sébastien, Guiu, Séverine, Levy, Christelle, Heudel, Pierre Etienne, Bachelot, Thomas, D’Hondt, Véronique, Darlix, Amélie, Firmin, Nelly, Romieu, Gilles, The

Journal:

Breast Cancer Research and Treatment

Année:

2016

Langue:

english

Fichier:

PDF, 1.31 MB

english, 2016

9

Bevacizumab Efficacy Is Influenced by Primary Tumor Resection in First-Line Treatment of Metastatic Colorectal Cancer in a Retrospective Multicenter Study

Cabart, Mathilde, Frénel, Jean-Sébastien, Campion, Loïc, Ramée, Jean-François, Dupuis, Olivier, Senellart, Hélène, Hiret, Sandrine, Douillard, Jean-Yves, Bennouna, Jaafar

Journal:

Clinical Colorectal Cancer

Année:

2016

Langue:

english

Fichier:

PDF, 599 KB

english, 2016

10

Le statut KRAS n’influence pas l’efficacité de l’oxaliplatine ou de l’irinotécan, en association au bévacizumab, dans le traitement de première ligne du cancer colorectal métastatique

Cabart, Mathilde, Frénel, Jean-Sébastien, Campion, Loïc, Ramée, Jean-François, Dupuis, Olivier, Senellart, Hélène, Hiret, Sandrine, Douillard, Jean-Yves, Bennouna, Jaafar

Journal:

Bulletin du Cancer

Année:

2016

Fichier:

PDF, 1.13 MB

2016

11

Vinflunine for the treatment of breast cancer

Gourmelon, Carole, Bourien, Héloïse, Augereau, Paule, Patsouris, Anne, Frenel, Jean-Sébastien, Campone, Mario

Journal:

Expert Opinion on Pharmacotherapy

Année:

2016

Langue:

english

Fichier:

PDF, 529 KB

english, 2016

12

Clinical Insights: Neoadjuvant Therapy in Breast Cancer || Multiple choice questions: ANSWERS

Campone, Mario, Frenel, Jean-Sébastien

Année:

2014

Langue:

english

Fichier:

PDF, 169 KB

english, 2014

13

Olaparib for the treatment of breast cancer

Robert, Marie, Frenel, Jean-Sébastien, Gourmelon, Carole, Patsouris, Anne, Augereau, Paule, Campone, Mario

Journal:

Expert Opinion on Investigational Drugs

Année:

2017

Langue:

english

Fichier:

PDF, 665 KB

english, 2017

14

ATIM-35. RESULTS OF THE PHASE IB KEYNOTE-028 MULTI-COHORT TRIAL OF PEMBROLIZUMAB MONOTHERAPY IN PATIENTS WITH RECURRENT PD-L1-POSITIVE GLIOBLASTOMA MULTIFORME (GBM)

Reardon, David A., Kim, Tae-Min, Frenel, Jean-Sebastien, Santoro, Armando, Lopez, Juanita, Subramaniam, Deepa S., Siu, Lillian L., Rodon, Jordi, Tamura, Kenji, Saraf, Sanatan, Morosky, Anne, Stein, Ka

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 67 KB

english, 2016

15

Efficacy of palbociclib plus fulvestrant after everolimus in hormone receptor-positive metastatic breast cancer

du Rusquec, Pauline, Palpacuer, Clément, Campion, Loic, Patsouris, Anne, Augereau, Paule, Gourmelon, Carole, Robert, Marie, Dumas, Laurence, Caroline, Folliard, Campone, Mario, Frenel, Jean-Sébastien

Journal:

Breast Cancer Research and Treatment

Année:

2017

Langue:

english

Fichier:

PDF, 1.10 MB

english, 2017

16

LTBK-04 FIRST RESULTS OF THE RANDOMIZED PHASE II STUDY ON DEPATUX –M ALONE, DEPATUX-M IN COMBINATION WITH TEMOZOLOMIDE AND EITHER TEMOZOLOMIDE OR LOMUSTINE IN RECURRENT EGFR AMPLIFIED GLIOBLASTOMA: FIRST REPORT FROM INTELLANCE 2/EORTC TRIAL 1410

van den Bent, Martin, Eoli, Marica, Sepulveda, Juan Manuel, Smits, Marion, Walenkamp, Annemiek, Frenel, Jean-Sebastien, Brandes, Alba A, Clement, Paul, French, Pim, Dubbink, Hendrikus, Kros, Johan, We

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 47 KB

english, 2017

17

An Update on the Clinical Use of CDK4/6 Inhibitors in Breast Cancer

Robert, Marie, Frenel, Jean-Sébastien, Bourbouloux, Emmanuelle, Rigaud, Dominique Berton, Patsouris, Anne, Augereau, Paule, Gourmelon, Carole, Campone, Mario

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 866 KB

english, 2018

18

Emerging PARP inhibitors for treating breast cancer

Robert, Marie, Patsouris, Anne, Frenel, Jean-Sébastien, Gourmelon, Carole, Augereau, Paule, Campone, Mario

Journal:

Expert Opinion on Emerging Drugs

Année:

2018

Langue:

english

Fichier:

PDF, 956 KB

english, 2018

19

miR-370-3p Is a Therapeutic Tool in Anti-glioblastoma Therapy but Is Not an Intratumoral or Cell-free Circulating Biomarker

Nadaradjane, Arulraj, Briand, Joséphine, Bougras-Cartron, Gwenola, Disdero, Valentine, Vallette, François M., Frenel, Jean-Sébastien, Cartron, Pierre-François

Journal:

Molecular Therapy — Nucleic Acids

Année:

2018

Langue:

english

Fichier:

PDF, 1.49 MB

english, 2018

20

Patient-centered simulations to assess the usefulness of the 70-gene signature for adjuvant chemotherapy administration in early-stage breast cancer

Caruana, Emmanuel, Foucher, Yohann, Tessier, Philippe, Frenel, Jean-Sébastien, Classe, Jean-Marc, Dantan, Etienne

Journal:

Breast Cancer Research and Treatment

Année:

2019

Langue:

english

Fichier:

PDF, 685 KB

english, 2019

21

Pharmacokinetic drug evaluation of abemaciclib for advanced breast cancer

Robert, Marie, Frenel, Jean-Sébastien, Bourbouloux, Emmanuelle, Berton Rigaud, Dominique, Patsouris, Anne, Augereau, Paule, Gourmelon, Carole, Campone, Mario

Journal:

Expert Opinion on Drug Metabolism & Toxicology

Année:

2018

Langue:

english

Fichier:

PDF, 968 KB

english, 2018

22

ACTR-47. PATIENTS WITH EGFR AMPLIFICATION BUT WITHOUT EGFRvIII EXPRESSION HAVE IMPROVED BENEFIT COMPARED TO THOSE WITH EGFRvIII EXPRESSION IN SAMPLES OF THE INTELLANCE 2/EORTC 1410 RANDOMIZED PHASE II TRIAL

French, Pim, Kros, Johan, de Heer, Iris, Eoli, Marica, Sepulveda, Juan, Walenkamp, Annemiek, Frenel, Jean-Sebastien, Franceschi, Enrico, Clement, Paul, Weller, Michael, Ansell, Peter, Looman, Jim, Bai

Journal:

Année:

2018

Fichier:

PDF, 84 KB

2018

23

Safety and Efficacy of Pembrolizumab in Advanced, Programmed Death Ligand 1–Positive Cervical Cancer: Results From the Phase Ib KEYNOTE-028 Trial

Frenel, Jean-Sebastien, Le Tourneau, Christophe, O’Neil, Bert, Ott, Patrick A., Piha-Paul, Sarina A., Gomez-Roca, Carlos, van Brummelen, Emilie M.J., Rugo, Hope S., Thomas, Shari, Saraf, Sanatan, Rang

Journal:

Journal of Clinical Oncology

Année:

2017

Fichier:

PDF, 693 KB

2017

24

ACTR-47. PATIENTS WITH EGFR AMPLIFICATION BUT WITHOUT EGFRvIII EXPRESSION HAVE IMPROVED BENEFIT COMPARED TO THOSE WITH EGFRvIII EXPRESSION IN SAMPLES OF THE INTELLANCE 2/EORTC 1410 RANDOMIZED PHASE II TRIAL

French, Pim, Kros, Johan, de Heer, Iris, Eoli, Marica, Sepulveda, Juan, Walenkamp, Annemiek, Frenel, Jean-Sebastien, Franceschi, Enrico, Clement, Paul, Weller, Michael, Ansell, Peter, Looman, Jim, Bai

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 84 KB

english, 2018

25

Defining EGFR amplification status for clinical trial inclusion

French, Pim J, Eoli, Marica, Sepulveda, Juan Manuel, de Heer, Iris, Kros, Johan M, Walenkamp, Annemiek, Frenel, Jean-Sebastien, Franceschi, Enrico, Clement, Paul M, Weller, Michael, Ansell, Peter, Loo

Journal:

Année:

2019

Langue:

english

Fichier:

PDF, 1.76 MB

english, 2019

26

Current options and future possibilities for the systemic treatment of hepatocellular carcinoma

Raoul, Jean-Luc, Frenel, Jean-Sébastien, Raimbourg, Judith, Gilabert, Marine

Journal:

Hepatic Oncology

Année:

2019

Langue:

english

Fichier:

PDF, 971 KB

english, 2019

27

Étude rétrospective : chirurgie d’intervalle tardive post chimiothérapie versus après 3–4 cures dans le cadre de la prise en charge d’un cancer de l’ovaire localement avancé non opérable d’emblée

de Fréminville, Quiterie, Licaj, Idlir, Frenel, Jean-Sebastien, Hamel-Senecal, Lea, Thomas, Guy, Brachet, Pierre-Emmanuel, Coquan, Elodie, Leconte, Alexandra, Classe, Jean-Marc, Joly, Florence

Journal:

Bulletin du Cancer

Année:

2019

Fichier:

PDF, 1.68 MB

2019

28

A pharmacokinetic evaluation of alpelisib for the treatment of HR+, HER2-negative, PIK3CA-mutated advanced or metastatic breast cancer

Bertho, Marion, Patsouris, Anne, Augereau, Paule, Robert, Marie, Frenel, Jean-Sebastien, Blonz, Cyriac, Campone, Mario

Journal:

Expert Opinion on Drug Metabolism & Toxicology

Année:

2020

Fichier:

PDF, 806 KB

2020